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Fu-Rong Du

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Review Open access Sep 2026

Patient-derived prostate cancer organoids: model development, therapeutic applications, and challenges for precision oncology

Prostate cancer ranks among the most prevalent male malignancies worldwide, with castration-resistant prostate cancer (CRPC) and drug resistance representing major clinical challenges. Conventional preclinical models fail to faithfully recapitulate tumor heterogeneity and the tumor microenvironment (TME). Patient-deriv...

Jing-Zhen Zhu, Sheng Wang, Fu-Rong Du et al. · 0 citations

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