Author

Fuyu Duan

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Open access Aug 2026

Repurposing a Small Molecule Plant Hormone as a Tunable ON‐Switch for CAR‐T Cell Immunotherapy

A novel inducible ON‐switch CAR design that leverages plant hormone signaling components to achieve controllable T cell activation allows rapid, reversible, and dose‐dependent T cell activation, resulting in potent cytotoxicity against B‐cell lymphoma in vitro and in vivo.

Hongxiang Zeng, Lei Zheng, Rongkun Tao et al. · Advancement of science · 0 citations

Aug 2026

Pattern-Filter structural validation of single-cell RNA-seq reads reduces artifactual barcodes and improves biological resolution.

These findings establish structural validation as an essential prerequisite for analysis, positioning Pattern-Filter as a useful standard for ensuring molecular fidelity and reliable biological discovery in single-cell transcriptomics.

Qiang Su, Xiao-Ming Zhou, Yi Long et al. · Genome Research · 0 citations