Author

G. Albano

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Open access Aug 2026

Structure of NHE6 and its lipid-mediated interactions regulating endosomal pH

Sodium-proton exchangers (NHEs) are found in all cells to regulate intracellular pH, sodium levels and cell volume. In humans, there are nine different NHE transporters (SLC9A1-9), which vary in tissue distribution, kinetics and regulation. NHE6 localizes to endosomal membranes and mutations in the protein are known to...

Suk-Han Jung, Hyunku Yeo, Hang Li et al. · Nature Communications · 0 citations