Background Insulin resistance–related metabolic burden is associated with cognitive aging, but the relevant white matter microstructural features remain unclear. We examined statistical indirect associations between metabolic indices and cognition through tract-level white matter measures, including associations with s...
Huai-Yi Li, Zhi-Liang Tian, Xiao-Qian Wang et al.· Frontiers in Neuroscience· 0 citations
Depression, anxiety, and higher odds of major cardiometabolic disorders were significantly associated, and IL-6 statistically mediated parts of these associations.
Asma Hallab, S. O'Bryant, Kristine Yaffe et al.· Scientific Reports· 0 citations
Exploratory factor analysis (EFA) identified clusters of correlated inflammatory biomarkers associated with cognitive performance in this cohort of midlife and older adults.
R. Singh, Semere Bekena, Alexis I. B. Walker et al.· Journal of Alzheimer's Disea...· 0 citations
Differential sensitivity of MRI biomarkers highlights the need for neuroimaging research tailored to diverse populations and supports integrating S/SDOH to inform precision-equity approaches to dementia prevention.
Yi-Qi Zhu, Alexis I. B. Walker, Semere Bekena et al.· Social Science & Medicine (1...· 0 citations
In older adults, HI was associated with MCI but not core AD biomarkers or future CDR progression, suggesting that late-life HI may reflect cognitive vulnerability or broader brain aging rather than independently driving AD pathology.
Semere Bekena, R. Singh, Subrata Pal et al.· Journal of Alzheimer's Disea...· 0 citations
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