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Author

G. Barbany

2 papers indexed here

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Open access Sep 2026

Diagnostic yield of cancer predisposition in a nationwide prospective childhood acute leukemia cohort

The utility of whole-genome sequencing (WGS) for detecting childhood leukemia predisposition remains unclear. We perform a nationwide, prospective, population-based study of 181 children with acute leukemia to assess diagnostic yield and clinical utility of a uniformly applied three-pronged strategy, including systemat...

F. Taylan, A. Staffas, Sara Sjögren et al. · 0 citations
Open access Sep 2026

Intense TP53 pathway selection drives clonal evolution from bone marrow failure to leukemia in ERCC6L2 disease

ERCC6L2 disease (ED) is an inherited bone marrow failure (BMF) syndrome that progresses almost exclusively to erythroid, TP53-mutated myeloid malignancy, but the somatic evolution underlying the progression in patients is unknown. We characterized the genetic landscape of 29 ED patients with longitudinal sampling, inte...

S. Douglas, I. Kaaja, I. Ikonen et al. · 0 citations

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