G. Batiha

Platelet-activating factor in multiple sclerosis: From peripheral inflammation to central neurodegeneration.

Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disease in which peripheral immune activation, blood-brain barrier (BBB) dysfunction, and central nervous system (CNS) injury are closely interconnected. Platelet-activating factor (PAF) is a potent phospholipid mediator involved in inflammation, p...

Targeting the α7-nicotinic acetylcholine receptor in multiple sclerosis: Implications for immunomodulation and neuroprotection.

Prenatal Paracetamol Exposure and Autism Spectrum Disorder: A Critical Review of Proposed Mechanisms, Epidemiological Evidence, and Causal Inference.

Overall, current evidence does not support a significant increase in ASD risk, and clinical guidelines should remain unchanged, given the known risks of alternative therapies, particularly non-steroidal anti-inflammatory drugs during pregnancy.

Epigenetic Regulation of Host Immunity During Parasitic Infections: Mechanisms, Immune Evasion, and Therapeutic Opportunities.

INTRODUCTION Parasitic infections remain a major global health challenge involving complex interactions between pathogens and host immunity. Emerging evidence indicates that epigenetic mechanisms, including DNA methylation, histone modifications, chromatin remodeling, and non-coding RNAs, critically regulate immune res...