G. Bertin

Global Proteomic Profiling of Cerebral Malaria-Infected Erythrocytes Reveals a specific PfEMP1 Expression Pattern.

Cerebral malaria (CM) is the most lethal complication of malaria, causing severe impairment of brain function. Although the precise mechanisms leading to CM remain unknown, the adhesion of infected erythrocytes to the cerebral endothelium, mediated by PfEMP1 proteins, is considered a key factor. These proteins, encoded...