Author

G. Caravagna

2 papers indexed here

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Review Sep 2026

A guide to understanding tumour evolution through the lens of population genetics.

It is argued that population genetics provides the mathematical framework needed to extract evolutionary dynamics from cancer genomes and it is shown how models of mutation, selection and drift transform allele frequencies from descriptive measurements into quantitative estimates of clonal fitness and evolutionary timi...

G. Caravagna, Trevor A. Graham, A. Sottoriva · Nature Reviews. Cancer · 1 citation

Open access Jul 2026

Gene mutant dosage is associated with prognosis and metastatic tropism in 60,000 clinical cancer samples

An open-source Bayesian inference tool that determines the multiplicity and copy number of driver mutations from tumor sequencing datasets is presented, an open-source Bayesian inference tool that determines the multiplicity and copy number of driver mutations from tumor sequencing datasets.

N. Calonaci, E. Krasniqi, D. Čolić et al. · Nature Genetics · 0 citations