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Author

G. Catucci

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Open access Sep 2026

Effect of Linker Sequence on the Interdomain Dynamics of Self-Sufficient CYP116B5-SOX Chimeras

In this work, the design of CYP116B5-SOX(PPII) is presented. This is an artificial self-sufficient enzyme in which the P450 116B5 peroxygenase and the H2O2-generating sarcosine oxidase (SOX) are linked together in a fusion complex. A polyproline type II helix (PPII) linker was used to connect the two enzymes, obtaining...

Daniele Giuriato, Lorenzo Gorga, S. Castrignanò et al. · 0 citations
Open access Aug 2026

Environmentally Persistent Pesticides: In Vitro Effects on Human Aromatase Activity and ERα Signaling

The presence and persistence of pesticides represent a concern for public health due to their potential activity as endocrine disrupting chemicals (EDCs) by interfering with hormone synthesis and signaling, leading to severe effects on human well-being. This work investigates the activity of a series of pesticides dete...

Francesca Armellino, Sabrina Costa, Francesco Giaretto et al. · 0 citations

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