Author

G. Çiftçi

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Open access Aug 2026

Investigation of the In Vitro and In Silico Anticancer Potential of Novel 4‐Arylthiazole‐Hydrazone Derivatives

The novel 4‐aryl‐2‐hydrazinothiazole derivatives synthesized and evaluated for their anticancer activity in MCF‐7 breast cancer, A549 lung cancer, and L929 normal cell lines were found to exhibit high cytotoxicity, particularly showing more selective and high‐potential antiproliferative activity on the MCF‐7 cell line.

Zeynep Zişan Demirci, Erol Akgün, G. Çiftçi et al. · Chemical Biology and Drug De... · 0 citations

Aug 2026

Development of thiazole-hydrazone hybrids for targeted therapy of non-small cell lung cancer.

Flow cytometry analyses revealed that these agents induced apoptosis and G0/G1 cell cycle arrest, indicating that their cytotoxic effects are mediated through these mechanisms, highlighting the potential of thiazolyl hydrazones as targeted therapeutic agents, warranting further investigations for NSCLC treatment.

M. Altıntop, Ipek Ertorun, Gülşen Akali̇n Çi̇ftçi̇ et al. · Bioorganic chemistry (Print) · 0 citations