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Review Open access Sep 2026

Need for Medication Review and Deprescribing in People Living with HIV: A Longitudinal Observational Study

Background/Objectives: People Living with HIV (PLWH) often have comorbidities require polypharmacy, increasing the risk of adverse events (AEs) associated with drug–drug/drug–supplement interactions (DDIs/DSIs). However, DDIs and DSIs, including those involving antiretrovirals (ARVs), and their related effects have not...

E. de Bellis, Danilo Donnarumma, Annarita Pagano et al. · 0 citations
Clinical trial Open access Aug 2026

Physical exercise for prevention of dementia study: a 48-month randomized controlled trial

Background Although multimodal exercise interventions are recognized for their potential to attenuate age-related cognitive decline, the current literature lacks longitudinal depth. Specifically, robust randomized evidence addressing the long-term efficacy of structured training protocols remains limited. This single-b...

E. Iuliano, G. Fiorilli, A. Angiolillo et al. · 0 citations
Open access Sep 2026

Intrinsic capacity is associated with cardiovascular rehabilitation outcome in older adults: a multidimensional comparison with frailty

Among older adults undergoing in-hospital CR, IC was more strongly and consistently associated with functional outcome than FI, particularly when vitality was operationalized through handgrip strength, and these findings support incorporating IC assessment into the multidimensional evaluation of older CR candidates.

L. Bencivenga, Annachiara Vassallo, G. Curcio et al. · 0 citations
Open access Jul 2026

Assessment of Causes and Potential Prevention and Therapy for Autoimmune Diseases Through Evolutionary Medicine

It is necessary to move beyond the concept of macroparasites as harmful species by definition and therefore to be eliminated without hesitation and consider the balances of its ecosystems before modern alterations, which is essential to study the holobiont as a whole and consider the balances of its ecosystems before m...

G. Libertini, G. Corbi, Valeria Conti et al. · 0 citations

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