Review
Open access
Oct 2026
Metabolic rewiring at the obesity–estrogen–polyamine axis in endometrial cancer: emerging mechanisms and translational opportunities
Endometrial cancer is one of the gynecologic malignancies most strongly associated with obesity, yet the biological basis of this association extends beyond excess adiposity as a risk factor. Obesity reshapes the endometrial ecosystem through peripheral estrogen excess, progesterone imbalance, insulin resistance, adipo...
D. Simancas-Racines, Dolores Jima Gavilanes, Andri Matos et al.
· Frontiers in Cell and Develo... · 0 citations