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Author

G. D. de Ferrari

4 papers indexed here

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Aug 2026

Cumulative Benefit With Evolocumab in Patients With No Prior Myocardial Infarction or Stroke in the VESALIUS-CV Study.

BACKGROUND Proprotein convertase subtilisin/kexin type 9 inhibition with evolocumab reduced the risk of a first major adverse cardiovascular event (MACE) in patients at high cardiovascular risk with no prior myocardial infarction (MI) or stroke in the VESALIUS-CV (Effect of Evolocumab in Patients at High Cardiovascular...

José C. Nicolau, Sabina A. Murphy, Robert P. Giugliano et al. · 1 citation
Open access Aug 2026

Effects of Evolocumab on Mortality Outcomes in Patients Without Previous Myocardial Infarction or Stroke: A Prespecified Analysis of the VESALIUS-CV Randomized Clinical Trial.

BACKGROUND Evolocumab, a PCSK9 (proprotein convertase subtilisin-kexin type 9) inhibitor, significantly reduced the risk of cardiovascular events in patients without previous myocardial infarction or stroke in the VESALIUS-CV trial (Effect of Evolocumab in Patients at High Cardiovascular Risk without Prior Myocardial I...

Robert P. Giugliano, E. Bohula, A. Bellavia et al. · 0 citations
Open access Sep 2026

Gaps in lipid management among high-risk patients without prior MI or stroke: the VESALIUS-REAL global study.

BACKGROUND Real-world evidence on lipid-lowering therapy (LLT) use and low-density lipoprotein cholesterol (LDL-C) control in patients at high cardiovascular (CV) risk without prior myocardial infarction (MI) or stroke remains limited. We evaluated LLT use, treatment intensification, LDL-C monitoring, and LDL-C goal at...

Q. Chan, J. Cegla, U. Laufs et al. · 0 citations
Review Jul 2026

Large language models in sports cardiology: Challenges, governance, and human-in-the-loop integration.

It is argued that current evaluation paradigms inadequately capture the uncertainty-intensive nature of athlete cardiovascular assessment and proposed the text-proxy paradigm, a governance-oriented framework in which LLMs operate as semantic integration layers that process clinician-verified and structured outputs gene...

Stefano Palermi, A. Saglietto, F. d'Ascenzo et al. · 0 citations

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