Author

G. De Simone

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Open access Sep 2026

681. Transcranial magnetic stimulation reveals altered GABAergic and glutamatergic activity in treatment-resistant schizophrenia

Abstract Background Treatment-resistant schizophrenia (TRS), affecting roughly one-third of patients, shows poor response to standard antipsychotics and may reflect more severe or distinct neurophysiological disruptions compared to treatment-responsive cases. Prior evidence from imaging and other methods suggested cort...

A. Barone, G. Senerchia, G. De Simone et al. · International Journal of Neu... · 0 citations

Open access Aug 2026

A Potential Link Between Dyslipidemia and Inflammation in Patients with Schizophrenia: Insights from Sterols and HDL Profile Analysis

Dyslipidemia and inflammation are two hallmarks of schizophrenia (SCZ), but the link between these two conditions remains elusive. We studied 40 SCZ patients and 40 age- and sex-matched healthy controls (CTRL) analyzing serum total, low-density lipoprotein (LDL), and high-density lipoprotein (HDL) cholesterol. In addit...

S. Bagnasco, G. De Simone, G. Cernera et al. · International Journal of Mol... · 0 citations

Review Open access Sep 2026

Addressing fusiform gyrus dysfunction in schizophrenia, theory of mind, and implications for antipsychotics' response and resistance: A systematic review and critical appraisal.

BACKGROUND The Fusiform Gyrus (FG), a brain region relevant for the interaction between cognitive processes and emotional behavior, especially emotion recognition and interpretation of social cues, has been linked to the pathophysiology of schizophrenia conceptualized as a disorder of aberrant synaptic function and bra...

M. Ciccarelli, B. Mazza, A. Nasti et al. · Neuroscience and Biobehavior... · 0 citations