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Open access Aug 2026

The dystonia-associated Torsin1A sustains CLCC1 function in membrane fusion of the nuclear envelope for NPC biogenesis.

The conserved membrane protein Chloride Channel CLIC-like protein 1 (CLCC1) is identified as a Torsin1A interaction partner whose absence phenocopies membrane fusion defects caused by Torsin deletion inform a model of nuclear envelope membrane fusion and imply that modulating CLCC1 expression is a promising therapeutic...

D. Maslennikova, Harry J. M. Baird, Xinyue Ding et al. · 3 citations · ⚡1

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