White matter hyperintensities (WMH) are common radiological findings with diverse clinical outcomes, including absence of clinical symptom, cognitive decline and dementia. One potential explanation for these differences is that WMH could differentially disrupt specific white matter tracts and lead to alterations in str...
GenFAR, a modular deep learning framework that learns general, clinically informed features from brain MRIs, is introduced, showing that using the learned feature representation can substantially increase the sample efficiency of secondary deep learning training tasks and models, as well as improve their accuracy.
V. Bashyam, G. Erus, Jun-Hao Wen et al.· 0 citations
Among CU individuals, plasma p-tau217 was associated with subsequent MCI/dementia due to AD and showed the most extensive associations with longitudinal AD-related brain atrophy, compared with SPARE-BA or R-indices capturing subcortical, diffuse cortical, or perisylvian atrophy.
Murat Bilgel, Ishaan Shah, Jasmine M. Cooper et al.· medRxiv· 0 citations
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