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Sep 2026
Pancreatic ductal adenocarcinoma (PDAC) remains highly lethal, partly because its dense, heterogeneous stroma restricts drug delivery, promotes immune exclusion, and supports therapeutic resistance. Stromal targeting has, therefore, evolved from broad depletion towards biomarker-guided reprogramming and normalization s...
M. De Luca, Francesco Balestra, Giorgia Panzetta et al.
· Cells · 0 citations
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Open access
Jul 2026
BACKGROUND
Graph-based machine learning approaches, including Knowledge Graph Embedding (KGE) methods and Graph Neural Networks (GNNs), have emerged as powerful tools for modeling complex biomedical data. However, a systematic and clinically grounded comparison of these approaches across heterogeneous healthcare graphs...
P. Sorino, A. D. Bellis, Daniele Malitesta et al.
· BMC Medical Informatics and... · 0 citations
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