Author

G. Gilardi

3 papers indexed here

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Open access Sep 2026

Effect of Linker Sequence on the Interdomain Dynamics of Self-Sufficient CYP116B5-SOX Chimeras

In this work, the design of CYP116B5-SOX(PPII) is presented. This is an artificial self-sufficient enzyme in which the P450 116B5 peroxygenase and the H2O2-generating sarcosine oxidase (SOX) are linked together in a fusion complex. A polyproline type II helix (PPII) linker was used to connect the two enzymes, obtaining...

Daniele Giuriato, Lorenzo Gorga, S. Castrignanò et al. · ACS Omega · 0 citations

Open access Aug 2026

Environmentally Persistent Pesticides: In Vitro Effects on Human Aromatase Activity and ERα Signaling

The presence and persistence of pesticides represent a concern for public health due to their potential activity as endocrine disrupting chemicals (EDCs) by interfering with hormone synthesis and signaling, leading to severe effects on human well-being. This work investigates the activity of a series of pesticides dete...

Francesca Armellino, Sabrina Costa, Francesco Giaretto et al. · Chemical Research in Toxicol... · 0 citations

Open access Jul 2026

Bioactivity and Ecotoxicological Safety of Subcritical Water Extracts from Coffee Production Waste as a Multifunctional Biopesticide

Valorizing agro-industrial by-products within a circular bioeconomy provides sustainable alternatives to synthetic pesticides. This study evaluated a coffee production waste (CPW) aqueous extract, obtained via subcritical water extraction, as a multifunctional biopesticide. We assessed its chemical profile, antifungal...

Francesco Aloi, L. Boffa, S. V. Prieto et al. · Agriculture · 0 citations