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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

G. González-Burgos

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Sep 2026

Shared Transcriptional Features of Layer 3 Pyramidal Neurons Projecting to the Monkey Dorsolateral Prefrontal Cortex.

OBJECTIVE Layer 3 (L3) pyramidal neurons projecting to the primate dorsolateral prefrontal cortex (DLPFC) convey essential information for core cognitive processes. Alterations in these neurons could contribute to cognitive deficits in schizophrenia. This study was designed to determine whether DLPFC-projecting L3 pyra...

D. Arion, J. Enwright, F. Krienen et al. · 0 citations
Open access Sep 2026

Selective depletion of upper-layer somatostatin interneuron subtypes in schizophrenia

Schizophrenia (SCZ) is associated with cortical GABAergic dysfunction, but whether inhibitory interneurons are lost or persist in an altered molecular state remains unresolved. Here, we harmonized seven prefrontal post-mortem single-nucleus RNA-seq datasets onto a fine-grained taxonomy of cortical cell types and meta-a...

Nicole Endresz, M. Fafouti, K. Arbabi et al. · 0 citations
Review Open access Sep 2026

GABAergic interneurons in local circuits of primate prefrontal cortex.

Cortical GABAergic interneurons exhibit remarkable diversity of morphological, electrophysiological and molecular features, which underlies their specialized roles in circuit functions. Molecular characteristics have proven to be a reasonable starting point in the past for classification, grouping them into parvalbumin...

S. Pommer, D. Lewis, F. Krienen et al. · 0 citations
Open access Sep 2026

322. Dysregulation of Cav3.1 and Cav1.2 in vulnerable DLPFC pyramidal neurons: a mechanistic link to cognitive disorders

Abstract Background The recently evolved dorsolateral prefrontal cortex (DLPFC) is essential to higher cognition, working memory and abstract thought, with pyramidal cell microcircuits in layer III that are able to excite each other to keep information “in mind” without sensory stimulation1,2. However, these pyramidal...

D. Datta, S. Yang, G. González-Burgos et al. · 0 citations
Review Open access Aug 2026

Diversity of Layer 3 Pyramidal Neuron Properties Across Areas of the Primate Neocortex.

Evidence suggesting that L3PN morphology and physiology differ significantly across PFC, PPC and V1 in primates is reviewed, suggesting a primate-enhanced regional variability that may be the substrate for area-specific L3PN vulnerability in schizophrenia.

G. González-Burgos, R. Benavides-Piccione, A. Neef et al. · 0 citations

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