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Author

G. Issa

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2 papers indexed here

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Open access Aug 2026

Clinical outcomes associated with NPM1 mutations in newly diagnosed acute myeloid leukemia

Nucleophosmin 1‐mutated (NPM1mt) acute myeloid leukemia (AML) is associated with a relatively favorable prognosis though long‐term outcomes remain suboptimal without clear predictors identified by therapy.

Aziz Farhat, Georgina El Hajjar, H. Kantarjian et al. · 1 citation
Sep 2026

Acute Myeloid Leukemia With KMT2A Amplification: A TP53-Alteration-Enriched Subgroup Associated With Chromoanagenesis and Poor Prognosis.

KMT2A amplification (KMT2A-amp) is a rare but aggressive genomic abnormality in acute myeloid leukemia (AML), with limited characterization in prior studies. We retrospectively analyzed 96 patients with AML harboring KMT2A-amp, including 56 newly diagnosed (ND) and 40 relapsed/refractory (RR) cases, with a median age o...

Thura Win Htut, Wei-Ying Jen, G. Issa et al. · 0 citations

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