Dendrimers are highly branched nanoscale macromolecules with precisely tunable architectures that have emerged as transformative tools in cancer research. Their unique properties, such as high drug-loading capacity, multivalency, and surface tailoring ability, enable innovative applications in drug delivery, gene thera...
Davood Zaeifi, K. Jamialahmadi, G. Karimi· Biomaterials Science· 1 citation
The TLR4/MyD88 signaling axis serves as a central hub linking microbial- and damage-associated molecular patterns to oncogenic inflammation. Upon ligand engagement, MyD88 orchestrates two major downstream branches, including the canonical NF-κB pathway, which drives transcriptional programs for cell survival, prolifera...
Davood Zaeifi, K. Jamialahmadi, G. Karimi· Pharmacological Research· 0 citations
The p66Shc protein functions as a cellular stress sensor that facilitates the elimination of irreversibly damaged cells under physiological conditions. However, during chronic stress, this pathway becomes maladaptive, contributing to progressive tissue degeneration. The present study reviews the involvement of p66S...
Fatemeh Yarmohammadi, Sasan Shabani, G. Karimi· Human & Experimental Tox...· 0 citations
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