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Author

G. Kerkhof

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Open access Oct 2026

Testosterone Replacement Therapy in Adolescents and Young Adults With Prader-Willi Syndrome: Efficacy and Effects on Behaviour.

CONTEXT Hypogonadism in Prader-Willi syndrome (PWS) is associated with decreased bone mineral density (BMD) in male adolescents and adults. Testosterone Replacement Therapy (TRT) improves BMD and sexual maturation, but TRT could aggravate pre-existing challenging behaviour in male patients with PWS. OBJECTIVE To inve...

Wiebe R. Flamman, Demi J. Trueba-Timmermans, L. Grootjen et al. · 0 citations

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