Author

G. Kollmorgen

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Open access Sep 2026

Health-related factors and their impact on blood-based biomarkers of Alzheimer's disease

Background Health-related factors may influence blood-based biomarkers (BBBM) of Alzheimer's disease (AD). In this analysis, associations between modifiable factors and plasma biomarkers of neurodegeneration were investigated across the Alzheimer's disease spectrum and in cognitively healthy controls in a cerebrospinal...

Carolin I. Kurz, Marleen Taute, Paulina Tegethoff et al. · Aging Brain · 0 citations

Open access Aug 2026

Cognitive components derived from traditional neuropsychological tests and their associations with plasma p-tau217 and p-tau181 in mild cognitive impairment: a multisite analysis.

BACKGROUND Currently, no single biomarker can reliably identify preclinical Alzheimer's disease (AD), particularly at or before the mild cognitive impairment (MCI) stage. Given the heterogeneity of MCI, integrative approaches are needed to improve early risk stratification. OBJECTIVES (i) To derive robust latent cogn...

Ana S. Perez, Hugo L. Hammer, V. Andersson et al. · GeroScience · 0 citations

Open access Aug 2026

Neurobiological correlates of longitudinal grey matter volume changes in preclinical Alzheimer’s disease

In this large longitudinal sample of asymptomatic individuals, the Aβ-dominant biomarker component showed the strongest association with longitudinal GM atrophy and cognitive decline, beyond the effects of tau pathophysiology and neuroaxonal injury.

W. Pelkmans, R. Cacciaglia, Michalis Kassinopoulos et al. · Molecular Neurodegeneration · 0 citations