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Author

G. Ma

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Open access Jul 2026

Causal immune-inflammation mapping of the GERD-Barrett-adenocarcinoma cascade identifies FGF19-HLA-DR⁺ T-cell axis driving esophagogastric junction metaplasia.

BACKGROUND Gastroesophageal reflux disease (GERD), Barrett's esophagus (BE), and esophageal adenocarcinoma (EAC) form a recognized pathological continuum, but the causal immune and inflammatory processes driving progression remain incompletely defined. METHODS Summary-level genome-wide association study (GWAS) data w...

Yixin Liu, Zhipeng Gong, Yuwen Tan et al. · 0 citations
Review Open access Aug 2026

Advances in understanding the mechanisms underlying acquired resistance to third-generation tyrosine kinase inhibitors in non-small cell lung cancer

The persistent emergence of resistance underscores that current targeted therapies, while revolutionary, are primarily disease-modifying rather than curative, necessitating continuous innovation to overcome the inherent biological challenge of tumor adaptability and heterogeneity.

Gu-Ha A-Lai, Lian Li, G. Ma et al. · 0 citations

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