Open access
Sep 2026
Genetic variants of the leptin–melanocortin pathway in a clinically selected Greek cohort with severe early-onset obesity and hyperphagia: implications for precision obesity medicine
Background Rare genetic forms of obesity are characterized by severe, early-onset obesity and hyperphagia, often involving the leptin–melanocortin pathway. Although advances in genetic testing have improved the recognition of monogenic obesity, data from Southern European populations remain limited. We investigated the...
E. Kostopoulou, D. X. Spilioti, Nikolaos D. Pantzaris et al.
· Obesity Pillars · 0 citations