This review summarizes the main research applications of next-generation sequencing in sarcoma, with particular attention to mutation and variant discovery, fusion detection, biomarker development, assay validation, multi-omics integration, and the boundaries between exploratory research and clinical implementation.
A. De Vita, Sara Violani, G. Miserocchi et al.· Current Oncology Reports· 0 citations
RvD5 reduced PD-1 expression on T cells and PD-L1 expression on cancer cells, thereby restoring T cell antitumor functions by delaying their differentiation into Tex, and suppresses tumor growth by dampening inflammation and delaying T cell exhaustion within the TME.
Maria Tredicine, Simona D'Orazio, Nunzia Coletta et al.· Journal of Immunology· 0 citations
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