G. Ortiz-Hernández

CCN1 as a compartment-specific biomarker of active microenvironmental remodeling: evidence from bone repair, aging, inflammation, and cancer

Cellular communication network factor 1 (CCN1) is a secreted matricellular protein induced by growth factors, mechanical stress, hypoxia, and tissue injury and regulates diverse cellular processes through interactions with integrins, heparan sulfate proteoglycans, and extracellular matrix (ECM) components. Although pri...