Author

G. Pijlman

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Open access Oct 2026

Pre-splicing factors associate with UpA-rich RNA and limit flavivirus replication.

RNA affinity purification coupled with mass spectrometry is used to identify diverse host factors that preferentially bind UpA-high RNA sequences, revealing a novel antiviral role for splicing factors, linking their preferential association with UpA-rich RNA to the restriction of UpA-high viruses.

Joyce W. M. van Bree, Kristel Doets, Carmen van de Waterbeemd et al. · Molecules and Cells · 0 citations

Open access Aug 2026

Sequence Homology and Tissue Tropism Determine Superinfection Exclusion of Zika virus in Aedes aegypti Mediated by an insect-specific Binjari-Zika Virus Chimera

It is demonstrated that incorporation of Zika virus prM and E proteins into the ISF backbone enhances infection of the mosquito midgut following oral exposure, which enables direct inhibition of ZIKV infection after a subsequent infectious blood meal, and defines a replication-dependent, tissue-specific mechanism of IS...

Wessel Willemsen, Alyssa J. Peterson, Marleen Henkens et al. · bioRxiv · 0 citations