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Oct 2026

Frailty patterns in European surgical patients: The FRAGILE multicentre prospective cohort.

BACKGROUND Frailty represents a multidimensional decline in physiological reserve that increases vulnerability to surgical stress. Its perioperative dynamics and association with outcomes across diverse surgical populations remain insufficiently characterised. OBJECTIVE This study aimed to describe the prevalence of...

C. Aldecoa, A. Zorrilla-Vaca, J. Ripollés-Melchor et al. · 0 citations
Open access Sep 2026

Monitoring Mitochondrial Function With High-Resolution Respirometry During Ex-Situ Heart Perfusion.

BACKGROUND Due to the high adenosine-triphosphate (ATP) consumption of the myocardial tissue, cardiac function is dependent on efficient mitochondrial respiration. Ischemia and reperfusion injury (I/R) has a severe impact on the function of the mitochondrial respiratory system. Ex-situ heart perfusion (ESHP) can minimi...

L. Stastny, J. Hofmann, A. T. Meszaros et al. · 0 citations

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