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Open access Sep 2026

849. To avoid or not to avoid? Prefrontal integration of cortical inputs modulates extinction of avoidance

Abstract Background The medial prefrontal cortex (mPFC) has a well-established role in extinction learning, triggering plasticity and cellular inhibition via projections to the amygdala. Simple behavioral models such auditory threat (fear) conditioning demonstrate how the infralimbic (IL) mPFC inhibits amygdala output...

G. Quirk · 0 citations

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