Differential glycosylation in the envelope glycoprotein enhances DC-SIGN-mediated cell entry of the West African Ebolavirus Makona
ABSTRACT During the 2013–2016 West African Ebola virus (EBOV) Makona epidemic, genomic surveillance identified an A82V substitution in the viral glycoprotein (GP) early in the outbreak. This mutation was associated with increased infectivity and faster viral spread, yet the host factors underlying this enhanced transmi...