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Open access Aug 2026

Physiological Signatures Derived from Wrist Accelerometry Improve Detection of Isolated REM Sleep Behavior Disorder

Isolated REM sleep behavior disorder (iRBD) is the strongest prodromal marker of -synucleinopathies, but polysomnography is impractical for population-scale screening and questionnaires lack sufficient specificity. Beyond nocturnal movement, recently published models can derive sleep staging and other physiological sig...

A. Brink-Kjaer, Johanne Niman Abildgaard, N. Lorenzen et al. · 0 citations
Jul 2026

Serum hypoxia-inducible factors, heat shock proteins, and mitochondrial biomarkers in relation to neurocognitive performance in obstructive sleep apnea: a cross-sectional study.

STUDY OBJECTIVES Obstructive sleep apnea(OSA) is linked to impaired cognitive functions through a variety of underlying mechanisms. We investigated possible hypoxic, inflammatory and mitochondrial mediators of cognitive dysfunction in OSA. METHODS We prospectively enrolled 146 adult patients with OSA and 103 healthy...

G. Şenel, Pelin Sordu, M. Sahin et al. · 0 citations

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