EXPRESS: Longitudinal Circulating miRNA Profiling Identifies Pharmacodynamic Biomarkers of Remote Ischemic Conditioning in Acute Ischemic Stroke: A Translational Sub-Study of the Randomized TRICS-9 Trial.
Remote ischemic conditioning(RIC) is a promising neuroprotective strategy for ischemic stroke, but reliable pharmacodynamic biomarkers confirming its biological activity are lacking. In this translational sub-study of the multicenter randomized phase II TRICS-9 trial, we profiled five circulating microRNAs (miR-181b,mi...