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Author

G. Sivakumar

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2 papers indexed here

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Oct 2026

Genomic Amplification of CCNE1 Is Associated with an Immunosuppressive Tumor Microenvironment and Adverse Clinical Outcome in High-Grade Serous Ovarian Cancer.

High-grade serous ovarian cancer (HGSOC) is the most lethal gynecological malignancy, with a poor 5-year survival rate. Many patients also experience relapse of the disease due to chemotherapy resistance, highlighting an urgent need for new therapeutic modalities. Among the genomic alterations implicated in HGSOC progr...

Annapurna Vadaparty, D. Veeraiyan, G. Sivakumar et al. · 0 citations
Review Open access Aug 2026

Aberrant Signal Transduction Pathways in Pancreatic Ductal Adenocarcinoma: Current Perspectives on Molecular Targets

The review discusses the key genetic drivers of pancreatic carcinogenesis, including KRAS, TP53, CDKN2A, SMAD4, and BRCA1/2, and emphasizes the role of these genes as therapeutic biomarkers for the development of targeted molecular therapy.

S. Kaviya, G. Sivakumar, P. Anandhasankar · 0 citations

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