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Preprint Sep 2026

HERO: Histology Encoder for Robust Representation in Oncology

Foundation models trained on large pathology image corpora now provide strong, transferable representations for computational pathology. Over the past few years a series of such models has been released, each trained on more slides than the last; on standard classification and segmentation benchmarks, the leading model...

Zhi Li, E. Amidi, Ya-Ting Cheng et al. · 0 citations
Open access Sep 2026

Integrated clinicogenomic analysis reveals the evolution and metastatic tropisms of advanced colorectal cancer

SUMMARY We performed an integrated clinical and genomic analysis of over 7,000 consecutively sequenced colorectal cancer (CRC) samples to comprehensively characterize genetic drivers and metastatic tropisms of CRC. We find that genomic evolutionary changes, such as clonal mutations and oncogenic mutant allele imbalance...

Paolo Manca, H. Walch, Jierui Xu et al. · 1 citation

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