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G. T. Tasibekova

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Open access 2026

Electrophysiological analysis of purinergic signaling of microglia as an approach to studying the immune mechanisms of Alzheimer's disease

Neuroinflammation mediated by chronic microglial activation is considered a key factor in the pathogenesis of Alzheimer's disease (AD). Purinergic signaling, particularly P2X4 and P2X7 receptors activated by extracellular ATP, plays an important role in modulating microglial function. Understanding the ionic mechanisms...

G. T. Tasibekova, N. Novosolova, M. K. Zholdasova et al. · 0 citations

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