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Author

G. Tsourouflis

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Review Open access Sep 2026

Hyperforin as a Multifunctional Specialized Metabolite of Natural Origin for Chronic Diseases: From Molecular Mechanisms to Clinical Translation

Hyperforin, a polyprenylated acylphloroglucinol and major bioactive constituent of Hypericum perforatum L. (H. perforatum, St. John’s Wort), has attracted considerable interest because of its pleiotropic pharmacological properties. Although historically investigated primarily for its contribution to the antidepressant...

Efthymios Poulios, Souzana K. Papadopoulou, Exakousti-Petroula Angelakou et al. · 0 citations

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