Senescence-Associated Extracellular Vesicles in Skin Aging and Regeneration: From Pathophysiology to Therapeutic Opportunities.
Cellular senescence is an important factor which significantly impairs the homeostasis and regeneration capability of skin through causing chronic inflammation, degradation of the extracellular matrix, depletion of stem cells, and angiogenesis impairment. In addition to the already known senescence associated secretory...