What is this summary about?This summary describes the main findings of the MANEUVER clinical trial for pimicotinib, a once-daily treatment. The goal was to see if pimicotinib could significantly reduce tumor size after 24 weeks of treatment in clinical trial participants with tenosynovial giant cell tumor (TGCT) comp...
H. Gelderblom, Xiao-Hui Niu, S. Stacchiotti et al.· Future Oncology· 0 citations
Abstract Background Tenosynovial giant cell tumor (TGCT) is a locally aggressive neoplasm caused by colony-stimulating factor 1 (CSF1) gene dysregulation. Vimseltinib is an oral, switch-control tyrosine kinase inhibitor of the CSF1 receptor. In part 1 of the MOTION phase 3 trial, vimseltinib demonstrated statistically...
V. Bhadri, H. Gelderblom, S. Stacchiotti et al.· The Oncologist· 0 citations
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Background:
Patients with advanced sarcoma experience significant symptom burden from disease and treatment, contributing to emergency department (ED) visits and unplanned hospitalization. There are no US-based studies evaluating longitudinal health-related quality of life (HRQoL) assessments using patient-...
H. Alsharif, Yue Yu, Saurabh D. Chitnis et al.· JCO Oncology Practice· 0 citations
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