Jul 2026
Targeting of CH25H to boost p62-dependent autophagic degradation of α-synuclein in cell and mouse models of Parkinson's disease.
Insight is provided into the mechanisms underlying α-synuclein turnover and suggests promising avenues for disease-modifying interventions in synucleinopathies.
Xiwei Zhang, Rui-xue Han, Wen Zhang et al.
· Science Translational Medici... · 0 citations