Multimodal DeepSurv model with SHAP-based interpretation for predicting local failure in patients with brain metastases undergoing hypofractionated stereotactic radiotherapy
Objective Local Progression-Free Survival (LPFS) is an important clinical endpoint following hypofractionated stereotactic radiotherapy (HSRT) for brain metastases (BMs). However, accurate prediction of local failure risk remains challenging because conventional clinical factors do not fully capture tumor heterogeneity...