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Gaoyuan Zhao

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Open access Aug 2026

Total Synthesis of ent-Kaurenoic Acid Diterpenoids Enabled by Distal Conformational Control in Photoredox Radical Polyene Cyclization.

We report a divergent synthesis of ent-kaurenoic acid-derived diterpenoids enabled by a stereoselective photoredox radical polyene cyclization directed by distal conformational control. A chiral bicyclo[3.2.1]octane unit biases the reactive polyene conformation and controls stereochemical outcome remotely during cascad...

Jinbo Duan, Xiao-Qian He, Xingyue Qi et al. · 0 citations

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