Review
Open access
Sep 2026
Cognitive decline over time in myotonic dystrophy type 1: a systematic review of longitudinal studies
Background Myotonic Dystrophy Type 1 (DM1) is a multisystem genetic disorder and the most common muscular dystrophy in adults. Central nervous system involvement is well-documented in DM1, including cognitive impairment. Cross-sectional studies have described a heterogeneous neuropsychological profile; however, the tra...
Ainara Clemente-Fernández, Irati Larrañaga, Joana Garmendia et al.
· Frontiers in Neurology · 0 citations