Author

Gavin Hargrove

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Open access Aug 2026

Discovery of quinazoline-based dual RET/Aurora B inhibitors for non-small cell lung cancer.

The discovery of dual RET/AurB inhibitors with potent activity in NSCLC cells is reported, establishing a dual-targeted RET/AurB inhibition strategy that addresses complementary oncogenic vulnerabilities in NSCLC and provides a strong foundation for continued optimization and development.

Maha Hanafi, Baha’a Jabali, Daniel Armstrong et al. · Bioorganic chemistry (Print) · 0 citations