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Author

Ge-Fei Hao

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Open access Oct 2026

Design, synthesis, and evaluation of antifungal and antibacterial activities of novel quinazolinone-formononetin derivatives.

BACKGROUND Plant pathogenic fungi and bacteria cause substantial losses in agricultural production worldwide, and escalating resistance to conventional agrochemicals necessitates the development of novel, environmentally benign pesticides. Formononetin, a naturally occurring isoflavone, exhibits promising bioactivities...

Xiao-Yan Pan, Jun-Rong Song, Qing-Xue Hu et al. · 0 citations
Aug 2026

Novel Flavonol Derivatives Bearing a 1,2,3,4-Tetrahydroquinoline Moiety: Design, Synthesis, and Anti-Phytophthora capsici Activity.

Mechanistic studies revealed that Q8 disrupted cell membrane integrity and inhibited succinate dehydrogenase (SDH) activity, with computational simulations suggesting a higher binding affinity for SDH than fluopyram.

Qing-Xue Hu, Xiao-Ting Geng, Fang Tian et al. · 0 citations

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