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Author

Ge Zhang

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Open access Aug 2026

Microglia-targeted Panax notoginseng polysaccharide nanoparticles alleviate Alzheimer's disease via AMPK-mTOR/HIF-1α-mediated immunometabolic reprogramming

Alzheimer's disease (AD) is increasingly recognized as an immunometabolic disorder characterized by a self-reinforcing cycle of neuroinflammation and glycolytic reprogramming in microglia. Herein, we developed KPBIT@NPs, a microglia-targeted polysaccharide-based nanomedicine. Unlike many conventional nanocarriers that...

Ge Zhang, Liang Kong, Ruihan Guo et al. · 0 citations
Open access Aug 2026

AB4-Loaded Nanomicelle Hydrogel Promotes Targeting of the Dysregulated Diabetic Wound Microenvironment via Coordinated Multistage Repair

This nanocomposite hydrogel integrating a bioactive carrier with a therapeutic payload to enable coordinated intervention across multiple phases of diabetic wound repair offers a promising strategy for the treatment of chronic diabetic wounds.

Xue Shao, De-Jin Ma, Ya-Ni Zhang et al. · 0 citations

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