Background: Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system characterized by marked clinical heterogeneity. The phenotype of the first relapse has been investigated as a potential prognostic marker, particularly whether initial motor manifestations are associated wi...
Geane Vasconcellos de Vasconcelos, Nara Samara Silva Felipe dos Santos, Pedro Vítor de Brito Ferreira et al.· ANPAbstract_CBN26· 0 citations
Background: Levodopa therapeutic response depends on factors that determine the optimization of drug absorption and distribution. In this perspective, gastrointestinal disorders in Parkinson's disease (PD), such as constipation and gastroparesis, act as an important barrier to effective treatment, increasing the degrad...
Nara Samara Silva Felipe dos Santos, Geane Vasconcellos de Vasconcelos, Gabriel Teles de Oliveira Piñeiro et al.· ANPAbstract_CBN26· 0 citations
Background: Multiple sclerosis (MS) is a chronic immune-mediated disease and a leading cause of neurological disability in young adults. Although inflammatory activity early in the disease has been linked to worse outcomes, the independent impact of relapse burden before diagnosis on long-term disability remains unclea...
Pedro Vítor de Brito Ferreira, Luisa Dias Moreno Avarena, Lucca Borges Ornelas et al.· ANPAbstract_CBN26· 0 citations
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