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Author

Geeta J. Narlikar

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Open access Aug 2026

ATP-dependent reorientation on a nucleosome primes INO80 for DNA translocation

ATP-dependent chromatin remodeling enzymes play central roles in genome regulation by mobilizing nucleosomes. All remodelers except for one, position their core ATPase at an internal nucleosome location, superhelical location (SHL) 2, and translocate DNA from this site to alter nucleosome conformation. The exception, t...

Hao Wu, Upneet Kaur, Cheng-Min Li et al. · 0 citations

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