An H₂O₂/Acidic Microenvironment-Responsive Theranostic Nanoplatform Promotes Spinal Cord Injury Repair via MRI-Guided Synergistic Anti-Ferroptosis.
The secondary injury cascade following spinal cord injury (SCI) involves complex pathological processes, with the interplay between ferroptosis and oxidative stress serving as a key impediment to neural repair. Ferrostatin-1 (Fer-1), an inhibitor of ferroptosis, faces limitations in clinical translation due to its low...