Author

Gen-Ying Zhuang

2 papers indexed here

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Open access Jan 2026

Targeted Delivery of Triptolide Via Folate-Functionalized Pluronic Micelles Enhances Anti-Melanoma Activity by Inducing Reactive Oxygen Species Accumulation.

Melanoma remains a highly lethal malignancy, often associated with limited therapeutic efficacy and substantial systemic toxicity caused by conventional chemotherapy. Triptolide (TP) exhibits potent antitumor activity, but its clinical application is limited by poor aqueous solubility and a narrow therapeutic window. I...

Gen-Ying Zhuang, Yan-Li Chen, Xiu-Li Gao et al. · BioMed Research Internationa... · 0 citations

Aug 2026

A scRNA-seq-guided gelsolin-functionalized gelatin methacryloyl platform integrating structural support and immunomodulation for osteoarthritis repair.

Osteoarthritis (OA) is a debilitating degenerative joint disease characterized by the irreversible breakdown of articular cartilage and chronic synovial inflammation. Current clinical interventions are primarily palliative, failing to address the dual challenges of structural degradation and the hostile, inflammatory m...

X.-V. Huang, Shou-Jie Wang, Gen-Ying Zhuang et al. · International Journal of Bio... · 0 citations